Senna can refer to:
- Ayrton Senna (1960–1994), former Formula One driver who was a three-time World Champion. He drove for Toleman, Lotus, McLaren and Williams, dying in an accident at the 1994 San Marino Grand Prix. Uncle of Bruno Senna.
- Bruno Senna, (b. 1983), Formula One driver who currently drives for Williams, having previously driven for HRT and Renault. Nephew of Ayrton Senna.
- Senna (film), a 2010 documentary film about Ayrton Senna, directed by Asif Kapadia.