Schlesser can refer to two people:
- Jo Schlesser (1928–1968), entered three races, two with a Formula Two-spec March. Killed in a horrific accident at the 1968 French Grand Prix.
- Jean-Louis Schlesser (b. 1948), made one start, in the 1988 Italian Grand Prix for Williams, and notably took Ayrton Senna out of the race, spoiling McLaren's clean sweep of wins.